Research progress of Cefpodoxime proxetil application in pediatrics
10.3760/cma.j.issn.2095-428X.2019.18.019
- VernacularTitle: 头孢泊肟酯在儿科应用研究进展
- Author:
Guocheng ZHANG
1
;
Zhou FU
2
;
Xin SUN
1
Author Information
1. Department of Pediatrics, Xijing Hospital, the Fourth Military Medical University, Xi′an 710032, China
2. Children′s Hospital Affiliated to Chongqing Medical University, Chongqing 400014, China
- Publication Type:Review
- Keywords:
Cefpodoxime proxetil;
Pediatrics;
Study
- From:
Chinese Journal of Applied Clinical Pediatrics
2019;34(18):1429-1433
- CountryChina
- Language:Chinese
-
Abstract:
Cefpodoxime proxetil(CPDX-PR) is the third generation cephalosporin with high oral efficiency.It has strong anti-gram negative bacteria and-gram positive bacteria effects, with wide tissue distribution, long plasma half-time(T1/2), stable to lactamase, good tolerance, small therapeutic dose, few times of administration, definite cli-nical efficacy and other advantages.It is recommended for application in the treatment guidelines of foreign children with various infectious diseases.It is of great clinical significance to discuss the rational application of CPDX-PR oral preparation under the condition of severe bacterial drug resistance.This article reviews the pharmacological characteristics of CPDX-PR and the research progress in the treatment of common infectious diseases in pediatrics, so as to promote the research on the rational clinical application of CPDX-PR in China.
