Effect of early mobilization on gastrointestinal function and delirium in patients with mechanical ventilation of chronic obstructive pulmonary disease
10.3760/cma.j.issn.1008-6706.2019.17.003
- VernacularTitle: 早期活动对慢性阻塞性肺疾病机械通气患者胃肠功能及谵妄的影响
- Author:
Jinggang LIU
1
;
Guizhen ZHANG
;
Shuang CHEN
;
Suqiu MENG
;
Jihua LIU
;
Shengqiang YANG
Author Information
1. Department of Intensive Care Unit, Huxi Hospital Affiliated to Jining Medical College, the Central Hospital of Shanxian County, Heze, Shandong 274300, China
- Publication Type:Journal Article
- Keywords:
Pulmonary disease, chronic obstructive;
Respiration, artificial;
Ventilators, mechanical;
Early ambulation;
Gastrointestinal motility;
Delirium
- From:
Chinese Journal of Primary Medicine and Pharmacy
2019;26(17):2057-2060
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the effect of early mobilization on gastrointestinal function and delirium in patients with mechanical ventilation of chronic obstructive pulmonary disease(COPD).
Methods:A total of 87 mechanically ventilated patients with COPD who met the inclusion criteria were selected as subjects from April 2017 to March 2018 in intensive care unit(ICU) of Huxi Hospital Affiliated to Jining Medical College.The patients were divided into treatment group (44 cases) and control group (43 cases) by the random number table method.On the basis of the same conventional treatment, the treatment group received early mobilization.The incidence of acute gastrointestinal injury(AGI), duration of AGI, incidence of delirium, duration of delirium, days of mechanical ventilation and 28-day mortality were compared between the two groups.
Results:The incidence rate of AGI in the treatment group was lower than that in the control group[40.9%(18/44) vs. 62.7%(27/43)], and the duration in the treatment group was shortened[(3.95±1.62)d vs. (5.23±2.03)d], and the incidence rate of delirium in the treatment group was lower[54.5%(24/44) vs. 76.7%(33/43)], the duration of delirium in the treatment group was shortened[(2.36±0.9)d vs. (3.25±1.27)d], the mechanical ventilation time in the treatment group was decreased[(6.39±1.76)d vs. (7.56± 1.49)d], the differences were statistically significant(χ2=4.17, t=-2.280, χ2=4.744, t=-2.919, -3.358, all P<0.05). There was no statistically significant difference in the rate of 28-day mortality between the two groups[2.3%(1/43) vs. 9.3%(4/43), χ2=-1.984, P>0.05].
Conclusion:Early mobilization can reduce the incidence and duration of AGI and delirium in COPD patients with mechanical ventilation, reduce the severity of AGI, and shorten the time of mechanical ventilation.
