Diagnostic significance of non-specific diagnostic indicators for bacterial neonatal late-onset sepsis
10.3760/cma.j.issn.1008-6706.2019.16.011
- VernacularTitle: 非特异性诊断指标对细菌性晚发型新生儿败血症的诊断意义
- Author:
Wanjian ZHAO
1
;
Yuehua FENG
;
Junhua LI
;
Sufen CAO
Author Information
1. Department of Pediatrics, Langfang People's Hospital, Langfang, Hebei 065000, China
- Publication Type:Journal Article
- Keywords:
Sepsis;
Bacterial;
Late-onset;
White blood cell;
Platelet;
C-reactive protein;
Percentage of neutrophils;
Mean platelet volume;
Infant, newbow
- From:
Chinese Journal of Primary Medicine and Pharmacy
2019;26(16):1960-1964
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the diagnostic value of non-specific diagnostic indicators for bacterial neonatal late-onset sepsis.
Methods:A total of 55 children with bacterial neonatal late-onset sepsis in Langfang People's Hospital were selected as sepsis group.Another 67 cases of non-infected newborns were selected as control group.White blood cell, platelet and C-reactive protein were retrospectively analyzed for diagnostic value.Meanwhile, percentage of neutrophils and mean platelet volume were analyzed for diagnostic value.
Results:When the bacterial neonatal late-onset sepsis occurred, the sensitivity(41.8%), specificity(95.6%) and positive predictive value(92.0%) of C-reactive protein were high.The sensitivity(18.2%, 10.9%), positive predictive value(71.4%, 85.7%) of white blood cell and platelet were low, but specificity(94%, 98.5%) was high.The percentage of neutrophils [(62.01±22.16)] and mean platelet volume[(11.60±0.98)] were higher than those of the control group [(36.58±11.06), (10.88±0.95)], and the differences were statistically significant(all P<0.05).
Conclusion:C-reactive protein has greater diagnostic value for bacterial neonatal late-onset sepsis.The percentage of neutrophils and mean platelet volume have some diagnostic value.
