Cellular fibroma of the ovary containing Leydig cell hyperplasia: a case report.
- Author:
Bo Sung YOON
1
;
Seok Ju SEONG
;
Chong Taik PARK
;
Hyun PARK
;
Jeong Yun SHIM
;
Ji Young KIM
Author Information
- Publication Type:Case Report
- Keywords: Ovary; Fibroma; Leydig cells
- MeSH: Aged; Cellular Structures; Cytoplasm; Eosinophils; Female; Fibroma; Humans; Hyperplasia; Leydig Cell Tumor; Leydig Cells; Male; Ovary
- From:Journal of Gynecologic Oncology 2010;21(1):56-58
- CountryRepublic of Korea
- Language:English
- Abstract: Ovarian stromal tumors containing Leydig cell components are rare. Only a few cases of ovarian stromal Leydig cell tumors characterized by clusters of Leydig cells have been reported to date. Here, we present the first case report of a 65-year-old woman with a cellular fibroma of the ovary containing Leydig cell hyperplasia. Microscopic examination revealed the proliferation of spindle cells arranged in intersecting bundles with mild nuclear atypia and an average of 2-3 mitotic figures per ten high-power fields. Multifocal nests of polygonal cells with abundant eosinophilic cytoplasm and round nuclei were seen within the spindle cells. Final pathology of the tumor revealed a cellular fibroma including Leydig cell hyperplasia.
