Distribution characteristics of pathogens and related risk factors causing pulmonary infection in patients with cardiovascular diseases
10.3760/cma.j.issn.1008-6706.2019.15.013
- VernacularTitle: 心血管病患者并发肺部感染的病原菌分布特点及相关危险因素分析
- Author:
Jinjun ZHAI
1
Author Information
1. Department of Emergency, the People's Hospital of Shanxi Province, Taiyuan, Shanxi, 030012, China
- Publication Type:Journal Article
- Keywords:
Cardiovascular diseases;
Respiratory tract infections;
Distribution of pathogens;
Risk factors
- From:
Chinese Journal of Primary Medicine and Pharmacy
2019;26(15):1842-1845
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the distribution characteristics of pathogens and related risk factors in patients with cardiovascular disease complicated with pulmonary infection.
Methods:From June 2015 to October 2017, 252 patients with cardiovascular disease who were treated in the People's Hospital of Shanxi Province were selected.The number of patients complicated with pulmonary infection in the treatment process was counted, the distribution characteristics of pathogens in patients with pulmonary infection was analyzed.The relationship between gender, age, time in bed, smoking history, invasive operation, chronic obstructive pulmonary disease(COPD) and pulmonary infection in patients with cardiovascular disease were analyzed.Logistic regression analysis was used to analyze the risk factors of pulmonary infection in patients with cardiovascular disease.
Results:There were 32 cases of pulmonary infection in 252 patients with cardiovascular disease, the incidence rate of pulmonary infection was 12.70%.Forty-one strains of pathogens were isolated from the patients with pulmonary infection, among them, there was Gram negative bacteria with 27 strains, accounting for 65.85%, Gram positive bacteria with 10 strains, accounting for 24.39%, and 4 fungi with 4 strains, accounting for 9.76%.The incidence of pulmonary infection in patients with cardiovascular disease was not related to the gender of the patients(χ2=0.267, P>0.05). The incidence rates of pulmonary infection in patients with age≥60 years old, time in bed for more than 2 weeks, smoking history, invasive operation, COPD were significantly higher than those of age<60, time in bed for less than 2 weeks, no smoking history, no invasive operation, no COPD(χ2=7.076, 7.066, 4.764, 12.603, 7.805, all P<0.05). The logistic regression analysis showed that age≥60 years old, time in bed for more than 2 weeks, smoking history, invasive operation, COPD were independent risk factors of patients with cardiovascular disease complicated with pulmonary infection(OR=4.229, 3.397, 3.504, 4.82, 3.804, all P<0.05).
Conclusion:The main pathogens of pulmonary infection in patients with cardiovascular disease are Gram negative bacteria, followed by Gram positive bacteria, only a few fungi.Excessive age, excessively long time in bed, smoking history, invasive operation, COPD are risk factors for pulmonary infection in patients with cardiovascular disease.
