Effect analysis of pharmacist intervention in perioperative prophylactic application of antibiotics
10.3760/cma.j.issn.1008-6706.2019.15.009
- VernacularTitle: 药师干预在围术期预防应用抗菌药物中的效果分析
- Author:
Chenfang MA
1
;
Chunfei LUO
1
;
Jinfen YANG
1
;
Xinhua CUI
2
Author Information
1. Department of Pharmacy, Zhejiang Rongjun Hospital, Jiaxing, Zhejiang 314000, China
2. Department of General Surgery, Zhejiang Rongjun Hospital, Jiaxing, Zhejiang 314000, China
- Publication Type:Journal Article
- Keywords:
Surgical procedures, operative;
Intraoperative period;
Perioperative care;
Anti-bacterial agents;
Antibiotic prophylaxis;
Pharmacists;
Intervention studies;
Patient satisfaction
- From:
Chinese Journal of Primary Medicine and Pharmacy
2019;26(15):1826-1829
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the efficacy of pharmacist intervention in perioperative prophylactic application of antibiotics.
Methods:From August 2017 to August 2018, 148 cases received surgery in Zhejiang Rongjun Hospital were selected, using odd-even grouping method, the patients were divided into two groups, with 74 cases in each group.The control group used antibacterial drugs without pharmacists intervention, the observation group used antibacterial drugs through pharmacists intervention.The use of antimicrobial agents was compared between the two groups.
Results:The duration of prophylactic medication, the duration of hospitalization in the observation group were (2.59±0.24)d, (8.47±0.83)d, respectively, which in the control group were (3.76±0.36)d, (10.74±1.32)d, respectively, the differences between the two groups were statistically significant(t=23.262, 12.523, all P<0.01). The total cost of antibacterial drugs and the total drug cost in the observation group were (778.62±76.35)CNY, (3 036.75±302.11)CNY, respectively, which in the control group were (1 063.26±105.32)CNY, (4 698.64±1 452.28)CNY, respectively, and the differences between the two groups were statistically significant(t=18.823, 9.638, all P<0.01). The antibacterial drug use satisfaction of the observation group was 97.30%(72/74), which of the control group was 74.32%(55/74), the difference between the two groups was statistically significant(χ2=16.038, P<0.01).
Conclusion:The rational use of antibiotics can be promoted by pharmacist intervention in perioperative prophylaxis patients.
