Effect of dezocine preemptive analgesia in the reconstruction of nasal bone fracture
10.3760/cma.j.issn.1008-6706.2019.15.006
- VernacularTitle: 地佐辛超前镇痛用于鼻骨骨折整复术的效果观察
- Author:
Ying ZHOU
1
;
Gaosheng WEI
2
;
Rong LIU
3
;
Longying LIU
1
;
Yuguang LI
1
Author Information
1. Department of Stomatology, the 908th Hospital of Chinese People's Liberation Army Joint Logistic Support Force, Yingtan, Jiangxi 335000, China
2. Department of Ophthalmology and Otorhinolaryngology, Yingtan People's Hospital, Yingtan, Jiangxi 335000, China
3. Department of Anesthesiology, the 908th Hospital of Chinese People's Liberation Army Joint Logistic Support Force, Yingtan, Jiangxi 335000, China
- Publication Type:Journal Article
- Keywords:
Nasal bone;
Fractures, bone;
Fracture reduction;
Preanesthetic medication;
Anesthesia and analgesia;
Dezocine;
Hemodynamics;
Comparative study
- From:
Chinese Journal of Primary Medicine and Pharmacy
2019;26(15):1814-1817
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the safety and efficacy of dezocine preemptive analgesia in the reconstruction of nasal bone fracture.
Methods:From September 2016 to May 2018, 63 patients with simple nasal bone fracture admitted to the 908th Hospital of PLA Joint Logistics Support Force were selected in the study.The patients were divided into two groups by random number table method: dezocine group(n=32) and control group(n=31). The dezocine group was injected with dezocine before surgery, while the control group was injected with 0.9% sodium chloride solution.The differences of MAP, HR, SpO2 at different time points between the two groups were observed.And the difference of VAS/RSS during operation and 2 hours after surgery were also observed.
Results:There were no statistically significant differences in MAP, HR and SpO2 between the two groups at different time points(10 min before and 10 min after intramuscular injection) (all P>0.05). During operation and 20 min after operation, the MAP values of the control group were (110.1±16.38)mmHg and (105.28±14.81)mmHg, respectively, which were higher than those of the dezocine group [(102.35±14.25)mmHg and (101.25±13.12)mmHg)], the differences were statistically significant(t=2.259, 2.153, all P<0.05). There were no statistically significant difference in HR between the two groups at 10 min before and 10 min after intramuscular injection(all P>0.05). The HR in the control group during operation and at 20min after operation were (90.81±19.52)times/min, (77.25±18.25)times/min, respectively, which were faster than those in the dezocine group [(85.16±17.25)times/min, (71.36±16.15)times/min], the differences were statistically significant(t=2.074, 2.047, all P<0.05). There were no statistically significant differences in SpO2 between the two groups at different time points(all P>0.05). In the surgery, the RSS score of dezocine group[(4.3±0.6)points] was better than that in control group[(2.1±0.4)points], the difference was statistically significant(t=17.008, P<0.05). The VAS scores in the control group during operation and 20 min after operation were (2.3±0.5)points, (1.5±0.8)points, respectively, , which were lower than those in the control group [(5.5±0.7)points, (2.1±0.6)points](t=20.572, 3.277, all P<0.05).
Conclusion:Application of dezocine preemptive analgesia in the reconstruction of nasal bone fracture is effective and safe, the hemodynamics is stable and the analgesic effect is definite in the surgery.
