Diagnostic value of magnetic resonance imaging and hydrogen ion magnetic resonance spectroscopy for central neurocytoma
10.3760/cma.j.issn.1008-6706.2019.14.009
- VernacularTitle: 磁共振成像、氢质子磁共振波谱检查对中枢神经细胞瘤的诊断价值
- Author:
Tao FANG
1
;
Bin ZHU
2
Author Information
1. Department of Radiology, Quzhou People's Hospital, Quzhou, Zhejiang 324000, China
2. Department of Radiology, Quhua Hospital, Quzhou, Zhejiang 324000, China
- Publication Type:Journal Article
- Keywords:
magnetic resonance imaging;
hydrogen proton magnetic resonance spectroscopy;
central neurocytoma;
differential diagnosis
- From:
Chinese Journal of Primary Medicine and Pharmacy
2019;26(14):1696-1699
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To analyze the clinical value of magnetic resonance imaging (MRI) and hydrogen proton magnetic resonance spectroscopy (~1H-MRS) in the diagnosis of central neurocytoma (CNC).
Methods:From February 2010 to February 2018, the clinical data of 12 patients with CNC confirmed by surgery and pathology in Quzhou People's Hospital were retrospectively analyzed.All patients underwent MRI diagnosis before operation.Among them, 9 patients received ~1H-MRS check.
Results:In this group of 12 patients, 9 patients occurred in the 2/3 area of the lateral ventricle, 2 cases occurred in the posterior third of the lateral ventricle, 1 case occurred in the frontal lobe; 11 cases were solid tumors, and 1 case was cystic tumors.MRI showed plaque calcification in the tumor, distortion of vascular shadow, T1WI was equal low signal, T2WI was contoured mixed signal; 8 cases showed uneven light and moderate enhancement, 3 cases showed uneven enhancement, 1 case showed ring enhancement; 8 cases of ~1H-MRS showed a significant increase in choline peak (Cho), N-acetylaspartate (NAA) peak decreased, and Cho/NAA increased.Meanwhile, 1 case of glycine peak (Gly) increased.
Conclusion:CNC has specific MRI performance, and plays an important role in preoperative diagnosis and differential diagnosis.Combined with ~1H-MRS examination, it can grasp the tumor biochemical index and metabolism from the molecular level and improve the accuracy of preoperative diagnosis.
