Accuracy of SPECT/CT fusion imaging in differential diagnosis of benign and malignant spinal lesions
10.3760/cma.j.issn.1008-6706.2019.13.005
- VernacularTitle: 单光子发射计算机断层成像/CT融合成像技术对脊柱病变良、恶性鉴别诊断准确率分析
- Author:
Caixia AN
1
;
Wanchun ZHANG
;
Huixia GENG
;
Yahong LONG
;
Xiaomin LI
;
Le MA
Author Information
1. Department of Nuclear Medicine, Shanxida Hospital, Taiyuan, Shanxi 030032, China
- Publication Type:Journal Article
- Keywords:
Spinal lesion;
Tomography, emission-computed, single-photon;
Tomography, X-ray computed;
Malignant;
Benign;
Fusion imaging;
Specificity;
Sensitivity;
Accuracy;
False positive
- From:
Chinese Journal of Primary Medicine and Pharmacy
2019;26(13):1553-1556
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To analyze and discuss the clinical value of single photon emission computed tomography(SPECT)/CT fusion imaging in differentiating benign and malignant spinal lesions.
Methods:From January 2017 to January 2018, 70 cases with benign and malignant spinal lesions in Shanxida Hospital were studied.SPECT/CT fusion imaging and SPECT examination were used to compare the diagnosis results between the two groups.
Results:After SPECT diagnosis, a total of 98 bone metastatic lesions were detected, including 10 false positive lesions, 60 benign lesions and 28 false negative lesions.After SPECT/CT fusion imaging, there were 100 lesions, including 4 false positive lesions, 59 benign lesions and 37 false negative lesions.In this study, a total of 145 lesions were found in 70 patients with benign and malignant spinal lesions, including 95 benign lesions and 50 malignant lesions.The specificity, sensitivity and accuracy of SPECT/CT fusion imaging [95.79%(91/95), 92.00%(46/50), 93.79%(136/145)] were higher than those of the control group [82.11%(78/95), 64.00%(32/50), and 82.76%(120/145)], the differences were statistically significant(χ2=9.048, 11.422, 9.578, all P<0.05).
Conclusion:In the diagnosis of benign and malignant spinal diseases, SPECT/CT fusion imaging can accurately distinguish benign and malignant lesions, and clearly reflect the development of the disease, which lay a solid foundation for good treatment in the future.
