Establishment of a critical segmental bone defect model in a rabbit ulna
10.3760/cma.j.issn.1008-6706.2019.13.003
- VernacularTitle: 兔尺骨中段临界节段性骨缺损模型的建立
- Author:
Dongming ZHOU
1
;
Ye AO
2
;
Haidong ZHANG
1
;
Wensheng XU
1
Author Information
1. Department of Orthopedics, the First Affiliated Hospital of Baotou Medical College, Inner Mongolia University of Science and Technology, Baotou, Inner Mongolia 014010, China
2. Quality Control Office, the First Affiliated Hospital of Baotou Medical College, Inner Mongolia University of Science and Technology, Baotou, Inner Mongolia 014010, China
- Publication Type:Journal Article
- Keywords:
Fractures, ununited;
Ulna;
Bone defect;
Models, animal;
Rabbit;
Animal experimentation;
Length;
Randomized controlled trial
- From:
Chinese Journal of Primary Medicine and Pharmacy
2019;26(13):1545-1548
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To establish a critical segmental bone defect model in a rabbit ulna.
Methods:Twenty male New Zealand white rabbits were randomly assigned into 5 groups according to the digital table, and then 14, 15, 16, 17 and 18mm segmental defects(contained periosteum) were created in the middle part of ulna on both sides, respectively.At 6 and 12 weeks after surgery, the repair of segmental bone defects was evaluated by naked eyes, X-ray and histological examination.
Results:At 12 weeks after surgery, all of the segmental defects with the length of 14 and 15mm were completely repaired.But none of the defects with the length of 16, 17 and 18mm was repaired.
Conclusion:The length of critical segmental bone defect in rabbit ulna was 16 mm.
