Consensus definition and development of new-onset refractory status epilepticus and the related syndromes
10.3760/cma.j.issn.2095-428X.2019.13.018
- VernacularTitle: 新发难治性癫痫持续状态及相关综合征的共识定义及研究进展
- Author:
Jinping LIANG
1
Author Information
1. Department of Neurology, Children′s Hospital, Chongqing Medical University, Chongqing 400014, China
- Publication Type:Review
- Keywords:
New-onset refractory status epilepticus;
Febrile infection-related epilepsy syndrome;
Infantile hemiconvulsion-hemiplegia and epilepsy syndrome;
Super-refractory status epilepticus;
Consensus definition;
Clinical characteristics;
Autoimmune encephalitis
- From:
Chinese Journal of Applied Clinical Pediatrics
2019;34(13):1033-1037
- CountryChina
- Language:Chinese
-
Abstract:
New-onset refractory status epilepticus(NORSE) is a clinical syndrome, not a specific diagnosis of diseases in patients with new onset of refractive status epilepticus without active epilepsy or other preexisting relevant neurological disorders and is not associated with a clearly acute or active structrue, toxic or metabolic cause.Febrile infection-related epilepsy syndrome(FIRES) is a subcategory of NORSE, applicable for all ages, occurring in a prior febrile infection starting between 24 hours and 2 weeks before onset of refractory status epilepticus(RSE) with fever or not.Proposed consensus definitions are also applicable for infantile hemiconvulsion-hemiplegia and epilepsy syndrome, RSE, super-RSE, prolonged RSE and prolonged super-RSE.These consensus definitions will promote much more effective communication and multicenter research, and ultimately improve recognition and treatment of these conditions.
