Finite Element Analysis on Porous Scaffold with Different Materials to Repair Defects of Rabbit Femur under Immediate Loading
10.16156/j.1004-7220.2019.06.08
- VernacularTitle:不同材料多孔支架在即刻负载下修复 兔股骨缺损的有限元分析
- Author:
Ti YU
1
;
Ting LIU
1
;
Yuanding HUANG
1
;
Chao WANG
1
Author Information
1. Chongqing Municipal Key Laboratory of Oral Biomedical Engineering of Higher Education, Chongqing Key Laboratory of Oral Diseases and Biomedical Science, Affiliated Stomatological Hospital of Chongqing Medical University
- Publication Type:Journal Article
- Keywords:
porous scaffold;
biomedical materials;
immediate loading;
finite element analysis （FEA）
- From:
Journal of Medical Biomechanics
2019;34(6):E615-E622
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the biomechanical behavior of porous scaffold with different materials (Ti, Ta, PEEK, HA) for repairing rabbit femur defects under immediate loading by three-dimensional finite element analysis (FEA), so as to explore the best porous scaffold material from the perspective of biomechanics. Methods The CBCT combined with software such as Mimics, SolidWorks, Geomagic Studio, ANSYS were used to establish an immediate loading model for the repair of rabbit femur defects with porous scaffolds at different stages of bone healing. The stress and strain distributions on the scaffolds and the surrounding tissues were calculated. Results The maximum equivalent stress of porous scaffold decreased along with the bone healing. In the granulation tissue and fibrous tissue model, the ratio of the maximum equivalent stress to the yield strength of porous scaffold was: HA＞Ta＞PEEK＞Ti. The maximum equivalent stress of the HA porous scaffold was greater than its yield strength. The number of suitable strain elements in tissues around the porous scaffolds was: PEEK＞Ta＞Ti＞HA. The number of potential fracture strain elements in tissues around the porous scaffolds was: HA＞Ta＞PEEK＞Ti. Conclusions The HA porous scaffold could not bear the immediate load and guide bone healing well under immediate loading. The elastic modulus of PEEK porous scaffold was similar to that of bone tissues, which could preferably guide bone healing. PEEK was an ideal porous scaffold material under immediate loading. The research findings provide
