Analysis of Key Techniques in Development of Primary Standard of Classical Prescription of Chinese Medicine
10.13422/j.cnki.syfjx.20191549
- VernacularTitle: 经典名方物质基准研制的关键技术分析
- Author:
Qi-meng FAN
1
;
Peng HE
1
;
Hai-ying LI
1
;
Run-nan LIU
1
;
Yu-ting HE
1
;
Hui-hui LIANG
1
;
Wen-long LIU
1
;
Yi-qun ZHOU
1
;
Fu-yuan HE
1
Author Information
1. College of Pharmacy, Hunan Provincial Key Laboratory of Druggability and Preparation Modification for Traditional Chinese Medicine, Pharmaceutical Preparation Technology and Evaluation Laboratory of Modern Chinese Medicine, Laboratory of Supramolecular Mechanism and Mathematic-Physics Chracterization for Chinese Materia Medica, Hunan University of Chinese Medicine, Changsha 410208, China
- Publication Type:Research Article
- Keywords:
Chinese medicine;
classical prescription;
primary standard;
key technologies;
total quantum statistical moment;
supramolecular imprinting template;
fingerprint
- From:
Chinese Journal of Experimental Traditional Medical Formulae
2019;25(15):202-209
- CountryChina
- Language:Chinese
-
Abstract:
Research and development of classical prescription of Chinese medicine has become one of the hot spots in the research of traditional Chinese medicine (TCM), and the successful development of the primary standard is crucial to the application of the classical prescription of Chinese medicine. Primary standard of classical prescription is not only the benchmark to measure the quality of preparation of classical prescription, but also the material basis of whole prescription. The development and quality control mode of single component of western medicine is not suitable for the development of TCM preparation with integral medicinal function. Thus, it is very urgent to develop an exclusive research and development model for TCM. In order to break through the quality control technology of primary standard of classical prescription, and comprehensively and accurately elucidate the transmission rule of the component group value of medicinal materials-decoction pieces-primary standard of classical prescription with the present modern science and technology, the genetic polymorphism of TCM, extraction kinetics, total quantum statistical moment (similarity) method of fingerprint and supramolecular imprinting template were combined and applied to the development of primary standard of classical prescription. In this way, the development and quality control of TCM will be realized in a real sense and the development of classical prescription of Chinese medicine will be accelerated and promoted.
