Mechanism of Chinese Material Medica in Treatment of Diabetes Mellitus Cerebral Infarction
- VernacularTitle: 中药复方治疗糖尿病合并脑梗死机制的研究进展
- Author:
Dong DENG
1
;
Shuang ZHOU
2
;
Miao-qing YE
1
;
Zhen-yi CHEN
1
;
Jian-hong BU
1
;
Li-hua SUN
1
;
Yun GENG
1
;
Wen ZHANG
1
;
Li-yang JIA
1
;
Bo PENG
1
;
Xiang WANG
1
;
Xin-zhu GUAN
1
;
Bang-jiang FANG
1
Author Information
- Publication Type:Research Article
- Keywords: traditional Chinese medicine compound; diabetes mellitus with cerebral infarction; mechanism of action; research progress
- From: Chinese Journal of Experimental Traditional Medical Formulae 2019;25(13):214-223
- CountryChina
- Language:Chinese
- Abstract: Diabetes mellitus complicated with cerebral infarction is the commonest and most serious vascular complication of diabetes mellitus. With a high disability and mortality rate, it seriously threatens human health. Because the pathogenesis is still unclear, more and more scholars have focused on the research of diabetic cerebral infarction at home and abroad. Traditional Chinese medicine(TCM) compounds have a remarkable curative effect in the treatment of diabetic cerebral infarction. Its mechanisms of action mainly include anti-hypertension, reduction of blood sugar and lipid, promotion of vascular regeneration and vascular endothelial function, anticoagulation, anti-thrombosis, improvement of nerve function defect, reduction of infarct volume, improvement of hemorheological, inhibition of inflammation and platelet aggregation, and promotion of collateral circulation. Through literature search, this paper summarizes the research progress of the mechanisms of TCM compounds in treating diabetic cerebral infarction in recent five years at home and abroad, in order to provide reference for clinical treatment.
