Clinical Efficacy of Wumeiwan Combined with Bazhentang in Treatment of Obese of Type 2 Diabetes Mellitus Patients with Qi and Yin Deficiencies, Phlegm and Stasis
10.13422/j.cnki.syfjx.20191225
- VernacularTitle: 乌梅丸合八珍汤加减治疗肥胖2型糖尿病气阴两虚夹痰瘀证临床观察
- Author:
Jie-hua HUANG
1
;
Xiao-min DENG
2
;
Cong CHEN
1
;
Geng-xu WU
1
;
Si-hua CHEN
1
;
Lan CHEN
1
;
Biao LUO
1
;
Dong SU
1
;
Ying TIAN
1
Author Information
1. Guangxi University of Chinese Medicine, Nanning 530001, China
2. The First Affiliated Hospital of Guangxi University of Chinese Medicine, Nanning 530023, China
- Publication Type:Research Article
- Keywords:
Wumeiwan;
Bazhentang;
obesity;
type 2 diabetes;
glucose metabolism;
lipid metabolism
- From:
Chinese Journal of Experimental Traditional Medical Formulae
2019;25(16):56-60
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To observe the clinical efficacy of Wumeiwan combined with Bazhentang in the treatment of obesity type 2 diabetes with Qi and Yin deficiencies, phlegm and stasis. Method: Totally 60 patients with type 2 diabetes mellitus were randomly divided into observation group and control group, with 30 cases in each group. Observation group was given Wumeiwan combined with modified Bazhentang in addition to Western medicine (metformin hydrochloride). The control group was treated with traditional Western medicine (metformin hydrochloride). The course of treatment is eight weeks. Fasting blood sugar (FPG),2 hPG (2 hPG),glycosylated hemoglobin (HbA1c),total cholesterol (TC),triglycerin (TG),body mass index (BMI),safety indicators (three major routine,liver and kidney functions) and clinical symptoms before and after treatment between two groups were compared. The clinical efficacy of two groups was evaluated. Result: The observation group had an effective rate of 93.3% (28/30),which was significantly higher than 73.3% (22/30) of the control group,with statistically significant differences (P<0.05). Compared with before treatment,the levels of FPG,2 hPG and HbA1c were significantly lower in two groups after treatment, and the treatment group was lower than control group (P<0.05). The levels of TC,TG,BMI and TCM syndromes were significantly reduced after treatment in two groups (P<0.05),and the levels of TC,TG,BMI and TCM syndromes were significantly lower than those in control group. The differences were statistically significant (P<0.05). Conclusion: Modified Wumeiwan combined with Bazhentang is safe and effective in treating patients with type 2 diabetes mellitus with Qi and Yin deficiencies, phlegm and stasis,and can reduce blood sugar,blood lipid,BMI level and relieve clinical symptoms of patients, and so worth promotion.
