Study on Stability of Volatile Oil in Foeniculi Fructus and Screening Its Antioxidants in Accelerated Oxidation Environment
10.13422/j.cnki.syfjx.20191348
- VernacularTitle: 加速氧化环境中小茴香挥发油的稳定性考察及其抗氧化剂筛选
- Author:
Jia TAI
1
;
Jun-bo ZOU
1
;
Ya-jun SHI
1
;
Dong-yan GUO
1
;
Xiao-fei ZHANG
1
;
Yu WANG
1
;
Yu-lin LIANG
1
;
Jing-lin LI
1
;
Jiang-xue CHENG
1
;
Ming YANG
2
;
Fang WANG
2
Author Information
1. Shaanxi Key Laboratory of Chinese Medicine Foundation and New Drugs Research, College of Pharmacy, Shaanxi University of Chinese Medicine, Xianyang 712046, China
2. Key Laboratory of Modern Preparation of Traditional Chinese Medicine(TCM), Ministry of Education, Jiangxi University of TCM, Nanchang 330004, China
- Publication Type:Research Article
- Keywords:
Foeniculi Fructus;
volatile oil;
stability;
antioxidants;
ascorbyl palmitate;
thiobarbituric acid reactive substances value;
peroxide value
- From:
Chinese Journal of Experimental Traditional Medical Formulae
2019;25(18):108-115
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To screen the accelerated oxidation environment with the most drastic changes in the volatile oil composition of Foeniculi Fructus, and to optimize the type and concentration of antioxidants. Method: The volatile oil of Foeniculi Fructus was extracted by steam distillation. Taking thiobarbituric acid reactive substances (TBARS) value and peroxide value (POV) as evaluation indexes, response surface method was used to investigate the effects of temperature, concentrations of ferrous ion (Fe2+) and azoamidine initiator V50 (AAPH) on volatile oil components of Foeniculi Fructus and its oxidation products. TBARS and POV were detected by ultraviolet chromatography. The oxidative environment with the most drastic changes of volatile oil composition of Foeniculi Fructus was screened. The type and concentration of antioxidants were selected by single factor experiments. The change discipline of volatile oil in Foeniculi Fructus after added different concentrations of antioxidants were analyzed by GC-MS. Result: The worst oxidizing environment for volatile oil of Foeniculi Fructus was as follows:temperature at 42.5℃,AAPH concentration of 1 g·L-1,Fe2+ concentration of 20.85 mg·L-1. Ascorbyl palmitate with concentrations of 0.2 mol·L-1 and 0.8 mol·L-1 could effectively improve the stability of volatile oil from Foeniculi Fructus. Conclusion: Under the accelerated oxidation environment, the terpenes in volatile oil from Foeniculi Fructus are significantly changed, but its stability can be improved by ascorbyl palmitate.
