Clinical Evaluation of Anesthetic Management for Pheochromocytoma Following Prazosin Pre-treament .
10.4097/kjae.1991.24.1.188
- Author:
Jung Suh KOO
1
;
Hyok Kwon KWON
;
Ok Hyun CHO
Author Information
1. Department of Anesthesiology, Dae Rim St. Mary's Hospital, Seoul, Korea.
- Publication Type:Case Report
- Keywords:
Pheochromocytoma;
Preoperative preparation;
Prazosin
- MeSH:
Anesthesia;
Arrhythmias, Cardiac;
Blood Pressure;
Female;
Fentanyl;
Hemodynamics;
Humans;
Incidence;
Middle Aged;
Pheochromocytoma*;
Prazosin*;
Propranolol;
Thiopental;
Vecuronium Bromide
- From:Korean Journal of Anesthesiology
1991;24(1):188-193
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Perioperative management of patients with pheochromocytoma is challenging. Accordingly, proper preoperative preparation is important. Prazosin, a selective alpha I blocker, may offer a potential advantage. This 54-year-old woman was treated with prazosin 2 mg, b.i.d. for 15 days and also with propranolol 20 mg, b.i.d. for a few days intermittently before the proposed surgery. Both symptoms and blood pressure were well controlled effectively. Induction of anesthesia was accomplished with nitrolingual spray, fentanyl 100 ug, 1% idocaine 50 mg, 2.5% thiopental sodium 200 mg, vecuronium 6 mg and 100% O2-enflurane. During the surgical and anesthetic procedure, the patient showed a reduced incidence of excessive blood-pressure variations and no arrhythmia was present except for supraventricular ectopic beats. Conclusively, we believe that careful preoperative preparation is recommended to minimize intraoperative hemodynamic dieturbances and their sequelae.
