Development and application of anti-human platelet and anti-thrombotic monoclonal antibodies
10.3760/cma.j.issn.1009-9921.2019.11.008
- VernacularTitle: 抗人血小板、抗血栓单克隆抗体的研制与应用
- Author:
Miao JIANG
1
;
Shundong JI
;
Kesheng DAI
;
Changgeng RUAN
Author Information
1. Key Laboratory of Thrombosis & Hemostasis of National Health Commission of the People's Republic of China, the First Affiliated Hospital of Soochow University, Jiangsu Institute of Hematology, National Clinical Medical Research Center of Blood Diseases, Suzhou 215006, China
- Publication Type:Journal Article
- Keywords:
Blood platelets;
Antibodies;
Thrombosis
- From:
Journal of Leukemia & Lymphoma
2019;28(11):676-677
- CountryChina
- Language:Chinese
-
Abstract:
Since its inception, anti-platelet antibodies have been an important tool for studying the interaction of platelets with blood components and blood vessels. At the same time, anti-platelet antibodies also play an important role in the detection and diagnosis of hemorrhagic and thrombotic diseases, and become a kind of powerful anti-thrombotic drugs. With the further understanding of the role of platelets in physiological hemostasis and pathological thrombosis, anti-platelet and anti-thrombotic antibodies also seek a balance between better anti-thrombotic effects and less bleeding side effects.
