Progresses of cathepsin S in kidney and rheumatic diseases
10.3760/cma.j.issn.1673-4408.2019.11.008
- VernacularTitle: 组织蛋白酶S在肾脏及风湿疾病中的研究进展
- Author:
Jingying ZHAO
1
;
Yubin WU
1
Author Information
1. Department of Pediatric Nephrology and Rheumatology, Shengjing Hospital of China Medical University, Shenyang 110004, China
- Publication Type:Review
- Keywords:
Cathepsin S;
Kidney and rheumatic disease
- From:
International Journal of Pediatrics
2019;46(11):806-809
- CountryChina
- Language:Chinese
-
Abstract:
Cathepsin S(Cat S) is an important member of the cysteine cathepsin protease family.It is a lysosomal protease, which has been shown to be expressed in inflammatory conditions and autoimmune diseases.It has more specific roles such as antigen presentation, tissue repair, cell proliferation and apoptosis.It contributes to a variety of clinical diseases.In this review, we summarize the structure, characteristics and functions of cathepsin S in kidney and rheumatic diseases.
