Progress in the diagnosis and treatment of multiple sclerosis
10.3760/cma.j.issn.1673-4408.2019.11.003
- VernacularTitle: 多发性硬化的诊断及治疗研究进展
- Author:
Chunying JIA
1
;
Mei LI
1
Author Information
1. Department of Neurology, Children′s Hospital of Chongqing Medical University, Chongqing 400014, China
- Publication Type:Review
- Keywords:
Multiple sclerosis;
Diagnosis;
Treatment;
Pediatric drug
- From:
International Journal of Pediatrics
2019;46(11):785-789
- CountryChina
- Language:Chinese
-
Abstract:
Multiple sclerosis is a chronic immune-mediated disease of the central nervous system.There is increasing incidence of MS globally, and the incidence of pediatric MS is relatively low.Environment and genetics both contribute to the causes of MS, while the specific etiology is unknown.MS is characterized by dissemination in time(DIT) and dissemination in space(DIS). Pathology is progressive since first attack, and the treatment is progressive even for a lifetime.The McDonald MS criteria was revised again in 2017 for diagnosing this disease earlier.Several drugs have been developed in recent years, and some drugs have guide of children dosage.However, treatment for children is still off-label.This article introduces the epidemiology, etiology, clinical presentation and pathology of MS.
