The analysis of the relationship between the fungal microbiota from soil and tongue coating of 18 patients with precancerous lesions of upper gastrointestinal
10.3760/cma.j.issn.0253-9624.2019.11.018
- VernacularTitle: 18例上消化道癌前病变患者舌苔与土壤真菌相关性分析
- Author:
Zhaolai HUA
1
;
Xian SUN
2
;
Chenyi WANG
2
;
Bin LU
3
;
Shuo XU
2
;
Chunjie XIANG
2
;
Junfeng ZHANG
2
;
Wenqiang WEI
4
Author Information
1. Yangzhong Cancer Institute, People′s Hospital of Yangzhong City, Yangzhong 212200, China
2. Medical School, Nanjing University of Chinese Medicine, Nanjing 210023, China
3. Department of oncology, People′s Hospital of Yangzhong City, Yangzhong 212200, China
4. Cancer Registry Office, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China
- Publication Type:Journal Article
- Keywords:
Precancerous conditions;
Tongue;
Soil;
Fungi;
Case-control studies
- From:
Chinese Journal of Preventive Medicine
2019;53(11):1166-1169
- CountryChina
- Language:Chinese
-
Abstract:
The fungal microbiota from self-retained soil and tongue coating of 18 patients with precancerous lesions of upper gastrointestinal (PLUG) were sequenced. The diversity of α, β in and the structure of the microbial community were analyzed, and the association of them was quantified by using the Spearman rank correlation method. The richness index (1.67±2.79) and the diversity index (0.25±0.10) of the fungal microbiota from tongue coating of PLUG patients were significantly lower than those from soil (4.00±4.69; 0.99±0.18) (all P values<0.001). The relative abundance of 11 taxa from tongue coating of these PLUG patients was positively associated with that from soil (all P values<0.05).
