Gender-specific factors of ischemic stroke among atrial fibrillation patients
10.3760/cma.j.issn.0253-9624.2019.11.012
- VernacularTitle: 不同性别心房颤动患者缺血型脑卒中的相关因素分析
- Author:
Jian GUO
1
;
Tianjia GUAN
1
;
Yuanli LIU
1
;
Baohua CHAO
2
;
Longde WANG
3
Author Information
1. School of Public Health, Peking Union Medical College, Beijing 100005, China
2. China Stroke Data Center, Beijing 100101, China
3. Peking University Health Science Center, Beijing 100083, China
- Publication Type:Journal Article
- Keywords:
Stroke;
Atrial fibrillation;
Risk factors;
Case-control studies
- From:
Chinese Journal of Preventive Medicine
2019;53(11):1136-1140
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore gender-specific factors and their contributions to ischemic stroke among atrial fibrillation (AF) patients.
Methods:A case-control study was conducted. The relevant data were obtained from the database of China National Stroke Screening Survey. The cases were first-ever ischemic stroke cases diagnosed from September 2013 to September 2015. Frequency-matched for the age and distribution of city and country, controls were randomly selected by 1∶3 ratio from individuals with AF but without stroke in the program. Altogether, there were 85 male cases (320 controls) and 147 female cases (484 controls). Unconditional logistic regression model was applied for the analysis of relevant factors of the onset of ischemic stroke, and their population-attributable risk proportion [PARP, (95%CI)] was calculated.
Results:The age of male subjects in the case group and control group were (65.26±11.20) and (64.83±11.08) years old, and that of females in two groups were (63.63±10.40) and (63.93±10.35) years old. According to the PARP (95%CI), relevant factors of the onset of ischemic stroke in a descending sequence were hypertension history [35.63 (18.64−47.73)], family history of stroke [28.70 (23.63−32.30)]and physical inactivity [15.73 [5.62−23.06)] among male AF patients, and family history of stroke (29.39 (24.21−33.08)), dyslipidemia (22.17 (2.26−36.45)) and smoking [2.09 (0.76−3.24)] among female AF patients.
Conclusion:The relevant factors of ischemic stroke were different between male and female AF patients.
