Standardized treatment of chronic radiation-induced bowel injury
10.3760/cma.j.issn.1671-0274.2019.11.004
- VernacularTitle: 慢性放射性肠损伤的规范化诊治
- Author:
Lei WANG
1
;
Tenghui MA
;
Zhihang LIU
;
Yanjiong HE
Author Information
1. Department of Colorectal Surgery, Radiation Enteropathy Specialty, Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases, the Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou 510655, China
- Publication Type:Journal Article
- Keywords:
Pelvic malignancy;
Radiation therapy;
Radiation-induced bowel injury, chronic;
Standardized diagnosis and treatment
- From:
Chinese Journal of Gastrointestinal Surgery
2019;22(11):1021-1026
- CountryChina
- Language:Chinese
-
Abstract:
Radiation-induced bowel injury is a common complication of radiation therapy for pelvic malignancy. Given the huge number of patients diagnosed with pelvic malignancy, the number of patients diagnosed with radiation-induced bowel injury increased year by year, which put a great burden on the clinical diagnosis and treatment of radiation-induced bowel injury. In particular, chronic radiation-induced bowel injury, which is manifested in the process of prolonged, repeated and progressive aggravation, seriously affects the physical and mental health of patients and makes clinical diagnosis and treatment difficult. However, due to insufficient attention and understanding from doctors and patients, standardized diagnosis and treatment of radiation-induced bowel injury still have a long way to go. Radiation-induced bowel injury is self-limited but irreversible. During diagnosis, we should pay attention to overall evaluation of the stage of disease based on clinical symptoms, endoscopic examination, imaging examination, pathology and nutritional risk. The treatment methods include health education, drug therapy, enema therapy, formalin local treatment, endoscopic treatment and surgical treatment, etc. The treatment decision-making should be based on clinical symptoms, endoscopic or imaging findings to alleviate the clinical symptoms of patients as the primary goal and to improve the long-term quality of life of patients as the ultimate goal.
