Value of the baseline Geriatric Nutritional Risk Index in evaluating the prognosis of maintenance peritoneal dialysis patients
10.3760/cma.j.issn.1001-7097.2019.11.007
- VernacularTitle: 基线老年营养风险指数对维持性腹膜透析患者预后的评估价值
- Author:
Afang LI
1
;
Yanna DOU
;
Peipei WANG
;
Bei ZHANG
;
Jing LUO
;
Dong LIU
;
Genyang CHENG
;
Jing XIAO
;
Zhangsuo LIU
;
Zhanzheng ZHAO
Author Information
1. Department of Nephrology, the First Affiliated Hospital of Zhengzhou University, Institute of Nephrology, Zhengzhou University, Zhengzhou 450052, China
- Publication Type:Clinical Trail
- Keywords:
Peritoneal dialysis;
Malnutrition;
Prognosis;
Geriatric nutritional risk index
- From:
Chinese Journal of Nephrology
2019;35(11):841-847
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the value of baseline geriatric nutritional risk index (GNRI) in evaluating the prognosis of patients with end-stage renal disease (ESRD) who underwent peritoneal dialysis (PD).
Methods:The clinical data of patients who underwent PD catheterization and started PD therapy at the First Affiliated Hospital of Zhengzhou University from January 1, 2013 to December 30, 2018 were collected retrospectively. The follow-up endpoint was death or hemodialysis. The follow-up deadline was March 1, 2019. The GNRI cut-off value was determined according to the ROC curve, and the patients were divided into GNRI≤90.5 group and GNRI>90.5 group. The differences of clinical data and laboratory tests were compared between the two groups. Kaplan-Meier survival curves were used to compare the difference in PD rate between the two groups during follow-up, and the factors that affecting patients PD withdrawal were analyzed by Cox regression.
Results:The GNRI cut-off value was determined to be 90.5 based on the ROC curve. Until the deadline for follow-up, the drop-out rate of GNRI≤90.5 group was significantly higher than the GNRI>90.5 group (35.88% vs 21.58%, P=0.003). Kaplan-Meier survival curves showed a higher rate of maintaining PD in the GNRI>90.5 group than that in GNRI≤90.5 group during follow-up (P=0.021). Cox univariate regression showed that male, GNRI and serum Alb were protective factors for PD patients, and Scr was a risk factor. After multiple factors correction, male and GNRI were also the protective factors for PD patients.
Conclusion:As an objective indicator of nutritional evaluation, baseline GNRI can be used as a prognostic indicator for PD patients.
