Effect of chronic hepatitis B virus DNA negative transformation and HBsAg clearance on the occurrence of hepatocellular carcinoma
10.3760/cma.j.issn.1007-3418.2019.11.004
- VernacularTitle: 慢性乙型肝炎HBV DNA阴转和HBsAg清除对肝细胞癌发生的影响
- Author:
Jialing ZHOU
1
;
Bingqiong WANG
;
Yiwen SHI
;
Hong YOU
Author Information
1. Liver Research Center, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China
- Publication Type:Journal Article
- Keywords:
Hepatitis, chronic B;
Carcinoma, hepatocellular;
Hepatitis B surface antigen seroclearance
- From:
Chinese Journal of Hepatology
2019;27(11):831-833
- CountryChina
- Language:Chinese
-
Abstract:
Achieving HBV DNA negative transformation and HBsAg clearance with effective antiviral therapy can reduce the incidence of HCC, but some patients are still at risk of developing HCC. Therefore, screening high-risk patients for close monitoring is essential to reduce the incidence of HCC. This paper reviews the occurrence of HCC, risk factors and risk prediction models of HBV DNA negative transformation and HBsAg clearance, and provides a basis for screening and follow-up management of high-risk group of HCC with chronic hepatitis B.
