Effect of Rosuvastatin on fasting plasma glucose after coronary stent implantation in elderly patients
10.3760/cma.j.issn.0254-9026.2019.11.006
- VernacularTitle: 瑞舒伐他汀对老年冠状动脉支架植入术后患者空腹血糖的影响
- Author:
Fangfang WU
1
;
Xiaoyan ZHAO
2
;
Jinling ZHANG
3
;
Zhengrong LI
4
;
Yuqiang WANG
1
;
Tao TIAN
5
Author Information
1. Department of Cardiology, Linyi People's Hospital, Shandong University, Linyi 276003, China
2. Department of Pharmacy, Chinese Medicine Hospital in Linyi City, Linyi 276002, China
3. Cerntral Laboratory, Linyi People's Hospital, Shandong University, Linyi 276003, China
4. Department of Pharmacy, Linyi People's Hospital, Shandong University, Linyi 276003, China
5. Department of Geriatrics, Linyi People's Hospital, Shandong University, Linyi 276003, China
- Publication Type:Journal Article
- Keywords:
Coronary artery disease;
Blood glucose
- From:
Chinese Journal of Geriatrics
2019;38(11):1216-1219
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the effect of Rosuvastatin on fasting plasma glucose after coronary stent implantation in elderly patients with non-diabetes mellitus.
Methods:A total of 216 non-diabetic elderly patients undergoing coronary stent implantation in our hospital from November 2015 to April 2018 were enrolled, with a follow-up in the cardiovascular department after discharge from the Hospital.The demographic data, follow-up time, and laboratory results at hospital admission and the last outpatient visit were collected retrospectively.
Results:At the end of follow-up, Fasting plasma glucose(FPG)was increased in 191 patients with normal baseline FPG level as compared with the baseline level(t=-3.783, P=0.000). The incidence of new-onset diabetes was higher in the pre-diabetes group than in the normal blood glucose group(24.0% vs.2.6%, χ2=16.72, P=0.000).
Conclusions:Rosuvastatin increases fasting blood glucose levels in elderly non-diabetic patients after coronary stent implantation.Pre-diabetes may increase the risk for rosuvastatin-associated new-onset diabetes.
