A comparative study on transnasal gastroscopy and conventional gastroscopy for percutaneous endoscopic pancreatic necrosectomy
10.3760/cma.j.issn.1007-5232.2019.11.005
- VernacularTitle: 鼻胃镜和常规胃镜在经皮内镜胰腺坏死组织清除术中的应用对比研究
- Author:
Yuanhang DONG
1
;
Chunhui JIANG
2
;
Wei GUO
3
;
Yanbo ZENG
1
;
Yiqi DU
1
Author Information
1. Department of Gastroenterology, Changhai Hospital, Naval Military Medical University, Shanghai 200433, China
2. Graduate School, Naval Military Medical University, Shanghai 200433, China
3. Department of Military Health Statistics, Naval Military Medical University, Shanghai 200433, China
- Publication Type:Journal Article
- Keywords:
Pancreatitis;
Percutaneous endoscopic necrosectomy;
Infective pancreatic necrosis
- From:
Chinese Journal of Digestive Endoscopy
2019;36(11):815-820
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To compare the therapeutic value of transnasal gastroscopy and conventional gastroscopy for infective pancreatic necrosis(IPN) through percutaneous endoscopic necrosectomy(PEN).
Methods:A total of 24 IPN patients who received PEN for IPN from December 2015 to March 2019 were divided into the conventional gastroscopy group (n=15) and the transnasal gastroscopy group (n=9). The clinical therapeutic indicators such as vital signs, APACHE Ⅱ score changes, operation duration, difference in preoperative and postoperative volumes of peripancreatic necrosis and other indicators were compared between the two groups.
Results:There was no significant difference in the variation curve fitting of APACHE Ⅱ scores between the two groups (t=0.378, P=0.710). The operation time of the transnasal gastroscopy group was significantly shorter than that of the conventional gastroscopy group (119.7±47.4 min VS 172.8±56.2 min, P=0.018). Peripancreatic necrotic volume significantly decreased after operation in the transnasal gastroscopy group (404.03±170.73 mL VS 468.9±137.37 mL, P=0.002), and in the conventional gastroscopy group (499.44±227.17 mL VS 722.50±292.96 mL, P<0.001). There was no significant difference in the decrease extent in the conventional gastroscopy group and the transnasal gastroscopy group (223.06±212.92 mL VS 64.87±54.94 mL, P= 0.094).
Conclusion:On the condition of poor drainage of percutaneous catheter drainage, PEN can significantly reduce the range of necrotic lesions. Transnasal gastroscopy has the advantages in operation time in PEN and clearing deep abscess cavities over conventional gastroscopy.
