A prospective study of optical coherence tomography for predicting invasion depth of early esophageal cancer
10.3760/cma.j.issn.1007-5232.2019.11.002
- VernacularTitle: 光学相干断层扫描技术判断早期食管癌浸润深度的前瞻性研究
- Author:
Jingyuan XIANG
1
;
Enqiang LINGHU
1
;
Longsong LI
1
;
Xiangyao WANG
1
;
Jiale ZOU
1
;
Hong DU
1
;
Ping TANG
1
;
Ningli CHAI
1
Author Information
1. Department of Gastroenterology, The First Medical Center of Chinese PLA General Hospital, Beijing 100853, China
- Publication Type:Journal Article
- Keywords:
Tomography, optical coherence;
Esophageal neoplasm;
Invasion depth;
Magnifying endoscopy with narrow band imaging;
Accuracy
- From:
Chinese Journal of Digestive Endoscopy
2019;36(11):802-805
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To evaluate optical coherence tomography(OCT)for predicting invasion depth of early esophageal cancer(EEC) and to compare OCT and magnifying endoscopy-narrow band imaging (ME-NBI)in clinical performance.
Methods:Twenty-eight patients who were diagnosed with EEC and accepted OCT and ME-NBI before endoscopic submucosal dissection(ESD)were enrolled in this prospective study. On the basis of OCT and ME-NBI images, real-time prediction of EEC invasion depth was conducted. Postoperative pathological results were taken as golden standard to compare the accuracy of OCT and ME-NBI in evaluation of EEC invasion depth. The procedure time and incidence of complications during evaluation process were also analyzed.
Results:The overall accuracy of OCT and ME-NBI in predicting invasion depth of 28 EEC patients were 67.9% (19/28) and 75.0% (21/28) respectively, with no significant difference(P>0.05). The accuracy of OCT and ME-NBI in distinguishing lesions located in epithelium/lamina propria mucosa (EP/LPM) lesions were 78.9%(15/19) and 68.4% (13/19), with no significant difference(P>0.05). The procedure time of OCT was significantly shorter than that of ME-NBI (6.0±2.9 min VS 16.3±5.4 min, P<0.001).
Conclusion:The ability of OCT to predict invasion depth of EEC and distinguish lesions located in the EP/LPM is comparable with that of ME-NBI. Besides, OCT requires shorter procedure time for evaluation.
