Progress of DNA methylation in the diagnosis and treatment of colorectal and lung cancer research
10.3760/cma.j.issn.1009-9158.2019.11.015
- VernacularTitle: DNA甲基化在结直肠癌和肺癌诊疗中的研究进展
- Author:
Dansheng LEI
1
;
Jing YU
Author Information
1. Department of Laboratory, Hubei Cancer Hospital, Hubei Clinical Research Center of Colorectal Cancer, Wuhan Clinical Research Center of Colorectal Cancer, Wuhan 430079, China
- Publication Type:Review
- Keywords:
Colorectal neoplasms;
Lung neoplasms;
DNA methylation;
Early diagnosis;
Treatment outcome;
Prognosis
- From:
Chinese Journal of Laboratory Medicine
2019;42(11):976-980
- CountryChina
- Language:Chinese
-
Abstract:
The incidences of colorectal and lung cancer are both increased in China while the treatment effect is far from satisfactory. As the rapid progress of epigenetic studies, DNA methylation has a series of promising research results in the pathogenesis, early diagnosis and treatment of tumor. A comprehensive understanding of its development status and existing problems is of great significance for the future research and the implementation of precision medicine. Herein, the aim is to outline the progress of DNA methylation in Colorectal and lung cancer and make a prospect for the future research.
