18F-FDG PET/CT imaging manifestations of peritoneal carcinomatosis from colorectal cancer and its clinical significance
10.3760/cma.j.issn.2095-2848.2019.11.003
- VernacularTitle: 结直肠癌腹膜转移的18F-FDG PET/CT影像学表现及其临床意义
- Author:
Chunfeng SUN
1
;
Zhonghua TAN
1
;
Yan GAO
1
;
Jianwei ZHU
2
;
Xiaoying MAO
1
;
Chengchun GE
1
;
Shanlei BAO
1
Author Information
1. Department of Nuclear Medicine, Affiliated Hospital of Nantong University, Nantong 226001, China
2. Department of Gastrointestinal Surgery, Affiliated Hospital of Nantong University, Nantong 226001, China
- Publication Type:Clinical Trail
- Keywords:
Colorectal neoplasms;
Neoplasm metastasis;
Peritoneum;
Positron-emission tomography;
Tomography, X-ray computed;
Deoxyglucose
- From:
Chinese Journal of Nuclear Medicine and Molecular Imaging
2019;39(11):653-656
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To analyze 18F-fluorodeoxyglucose(FDG) PET/CT imaging manifestations in patients with peritoneal carcinomatosis (PC) from colorectal cancer (CRC) and investigate its clinical significance.
Methods:From May 2016 to August 2018, 46 patients (25 males, 21 females; age range: 36-82(62.0±10.4) years) with PC from CRC who underwent 18F-FDG PET/CT imaging in Affiliated Hospital of Nantong University and had complete clinical data were retrospectively analyzed. The peritoneal carcinomatosis index (PCI) grading system was used to evaluate the PC lesions. Independent-sample t test and Kruskal-Wallis H test were used for data analysis.
Results:There were various CT manifestations of PC, while FDG metabolism on PET was observed in all 46 patients. Patients were divided into different groups according to the location of the primary CRC lesion. The diameter of PC lesion in the left colon group was (2.46±1.26) cm, which was significantly different from that of the rectum group ((3.19±1.72) cm; t=-2.77, P<0.01). The maximum standardized uptake value (SUVmax) in the right colon group were significantly higher than that in the left colon group (9.16±4.79 vs 6.99±3.50; t=2.92, P<0.01). The PCI score ranged from 1 to 30 in 46 patients, and there was no significant difference in PCI score distribution (≥20 vs <20) among the right colon group, left colon group and rectum group (H=0.242, P>0.05). Ten patients had abdominal and pelvic effusion.
Conclusion:18F-FDG PET/CT can well display the PC in patients with CRC, and the combination of PCI and 18F-FDG PET/CT plays an important role in the diagnosis and treatment of PC.