Effect of perioperative allogeneic red blood cells transfusion on early postoperative recurrence in patients with hepatocellular carcinoma
10.3670.cma.j.issn.1007-631X.2019.11.002
- VernacularTitle: 围手术期输血对肝细胞癌患者术后早期复发的影响
- Author:
Qibin SU
1
;
Yanyan WANG
1
;
Jianhong ZHONG
1
;
Lunan QI
1
;
Bangde XIANG
1
;
Lequn LI
1
;
Liang MA
1
Author Information
1. Department of Hepatobiliary Surgery , Affiliated Tumor Hospital of Guangxi Medical University, Nanning 530021, China
- Publication Type:Journal Article
- Keywords:
Carcinoma, hepatocellular;
Hepatectomy;
Red blood cells;
Recurrence
- From:
Chinese Journal of General Surgery
2019;34(11):916-920
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the impact of perioperative allogeneic red blood cells transfusion on the early recurrence of patients with hepatocellular carcinoma (HCC) after liver resection.
Methods:Retrospective analysis was made on 999 patients who underwent surgical resection for HCC, and these patients were divided into two groups according to whether or not received perioperative allogeneic red blood cells transfusion. Differences between groups were balanced using propensity score matching (PSM). The Kaplan-Meier method was used for comparing the differences in early recurrence (within 2 years) between the two groups and the multivariate COX analysis regression was used to identify independent risk factors for early recurrence.
Result:There were 100 patients in red cell transfusion group and 899 patients in non-red cell transfusion group. After PSM, 85 pairs of patients were successfully matched, and there was no significant difference in baseline data between groups. Before PSM, the early recurrence rate of the red blood cell group was significantly higher than that of the non-red blood cell group (P<0.05). However, there was no significant difference in early recurrence rates between the two groups after PSM (P=0.346). Multivariate analysis showed that perioperative allogeneic red blood cells transfusion was not an independent risk factor of early recurrence for patients with HCC after liver resection (P=0.153).
Conclusion:Perioperative allogeneic red blood cells transfusion has no impact on the early recurrence of patients with HCC after liver resection.
