Comparison in precision of image registration between MRI simulation and diagnostic MRI with CT simulation
10.3760/cma.j.issn.0254-5098.2019.11.005
- VernacularTitle: 磁共振模拟定位及磁共振诊断影像与定位CT融合的精准性比较
- Author:
Ying GU
1
;
Penfei XING
;
Shang CAI
;
Jianjun QIAN
;
Qiuhong FAN
;
Ye TIAN
Author Information
1. Department of Radiation Oncology, Second Affiliated Hospital of Soochow University, Institute of Radiotherapy & Oncology, Soochow University, Suzhou Key Laboratory for Radiation Oncology, Suzhou 215004, China
- Publication Type:Journal Article
- Keywords:
MRI simulation;
Image fusion;
Rigid registration;
MRI diagnosis;
Precision
- From:
Chinese Journal of Radiological Medicine and Protection
2019;39(11):827-832
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To evaluate the precision of image registration between MRI simulation (MRIsim) and CT simulation compared to diagnostic MRI(MRIdiag) and to provide information for further application of MRIsim.
Methods:A total of 24 patients who underwent both MRIsim and MRIdiag were enrolled, including 8 patients with gliomas, 8 with nasopharyngeal carcinomas and 8 with prostate cancers. MRIsim and MRIdiag images of each patient were fused with CT. The OARs were delineated on three modalities of images and targets were delineated on fusion image of MRIsim with CT (F_CTMsim) and fusion image of MRIdiag with CT (F_CTMdiag) respectively. The concordance index (CI), Dice′s similarity coefficient (DSC) between the OARs and image similarity index (S) based on images from MRIsim, MRIdiag and CT were evaluated. IMRT plans were designed based targets on F_CTMsim and OARs on CT images, and differences in dosimetry of targets and OARs were evaluated subsequently.
Results:Volumes of most OAR from three modalities of images showed no statistically significant difference(P>0.05). All the CI and DSC between the OARs derived from MRIsim and CT were higher than those corresponding values from MRIdiag, and a statistically significant difference was achieved in 50% of these OARs (t=2.58-5.47, P<0.05). The S values of MRIsim and MRIdiag compared with CT were 0.89 and 0.83 respectively (t=5.77, P<0.05). MRIsim improved the S value by 10% (2%-56%) compared with MRIdiag. No further differences in dosimetry were found on all OARs and all targets(P>0.05).
Conclusions:The precision of image registration can be significantly improved by introducing MRIsim into radiotherapy planning design compared with MRIdiag. However, no significant differences in dosimetry were found on targets produced by rigid registration and manual adjustment method .
