Epidemiological and clinical characteristics of hemorrhagic fever with renal syndrome in Qingdao, Shandong Province
10.3760/cma.j.issn.2095-4255.2019.11.016
- VernacularTitle: 山东省青岛市肾综合征出血热的流行病学及临床特征分析
- Author:
Ji LIU
1
;
Bin HAN
;
Xiaolin YIN
;
Hong HE
;
Lijing PENG
;
Lin WANG
Author Information
1. Department of Clinical Laboratory, the Affiliated Hospital of Qingdao University, Qingdao 266003, China
- Publication Type:Clinical Trail
- Keywords:
Hemorrhagic fever with renal syndrome;
Epidemiology;
Clinical features
- From:
Chinese Journal of Endemiology
2019;38(11):932-935
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the epidemiology and related clinical features of hemorrhagic fever with renal syndrome (HFRS) in Qingdao, and provide relevant evidence for clinical diagnosis and treatment.
Methods:The retrospective analysis method was used to collect the epidemiological and clinical data of 104 patients with HFRS diagnosed in the Affiliated Hospital of Qingdao University from January 2014 to December 2018, and the general condition, clinical symptoms, laboratory examination and exposure history of the patients were analyzed.
Results:One hundred and four patients with HFRS were aged from 10 to 87 years old, including 78 males and 26 females; mainly living in rural areas, accounting for 90.38% (94/104); and 54 cases from the Department of Nephrology, accounting for 51.92%. October to January of the following year was the main onset time, accounting for 68.27% (71/104). The clinical manifestations were 98 cases of fever, accounting for 94.23%; 66 cases of nausea and vomiting, accounting for 63.46%; and 57 cases of dizziness and headache, accounting for 54.81%. Laboratory examination showed more thrombocytopenia, urinary protein and occult blood positive, D-dimer elevation, C-reactive protein and procalcitonin elevation. Only 8 cases had a history of direct, indirect or suspicious contact.
Conclusions:The clinical features of HFRS are atypical. The main symptoms are fever, nausea and vomiting, dizziness and headache. Men are higher than women. The place of residence is mainly in rural areas. The exposure history is mostly unclear. Diagnosis should be combined with laboratory findings and early treatment to improve clinical outcomes.
