The 471st case: duodenal ulcer, mucor infection, and elevated IgG4
10.3760/cma.j.issn.0578-1426.2019.11.020
- VernacularTitle: 第471例——十二指肠溃疡，毛霉菌感染，血IgG4升高
- Author:
Zihan JIANG
1
;
Sihua LIU
2
;
Yao XIAO
2
;
Wei CAO
3
;
Weixun ZHOU
4
;
Wen ZHANG
5
;
Dong WU
6
Author Information
1. Department of Health Care & International Medical Services, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100730, China
2. Department of Clinical Medicine, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100005, China
3. Department of Infectious Diseases, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100730, China
4. Department of Pathology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100730, China
5. Department of Immunology and Rheumatology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100730, China
6. Department of Gastroenterology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100730, China
- Publication Type:Journal Article
- Keywords:
Mucor infection;
IgG4-related diseases;
Duodenal ulcer
- From:
Chinese Journal of Internal Medicine
2019;58(11):861-864
- CountryChina
- Language:Chinese
-
Abstract:
Mucor infection is rarely reported in non-immunocompromised population, especially in isolated gastrointestinal tracts. IgG4-related diseases (IgG4-RD) have been recognized in recent years, but secondary causes of IgG4 elevation should be differentiated. We reported a young man with duodenal mass and ulcer and high serum IgG4 level. Histological biopsy of the mass revealed positive mucor mycelium and infiltration of IgG4 positive plasma cells. Serum IgG4 decreased to normal range after surgical resection and systemic antifungal treatment. This case suggests that isolated mucor mycosis infection can develop in the digestive tract and mimics as IgG4-related disease.
