Effect of chemoradiotherapy on anti-tumor immunity of glioblastoma patients and treatment enlightement
10.3760/cma.j.issn.1006-9801.2019.12.016
- VernacularTitle: 放化疗对胶质母细胞瘤患者抗肿瘤免疫功能影响及治疗启示
- Author:
Mingxiao LI
1
;
Haihui JIANG
;
Song LIN
Author Information
1. Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing Institute of Neurosurgery, Beijing 100070, China
- Publication Type:Review
- Keywords:
Glioblastoma;
Immunotherapy;
Drug therapy, combination;
Radiotherapy
- From:
Cancer Research and Clinic
2019;31(12):855-857
- CountryChina
- Language:Chinese
-
Abstract:
Glioblastoma (GBM) is the most malignant primary brain tumor, and it has very poor prognosis. In recent years, the immunotherapy has become a hot issue in the treatment of malignancies. The traditional treatment regimen combined with immunotherapy might make a progress in the diagnosis and treatment of GBM. This paper reviews the explanation of the traditional chemoradiotherapy affecting the body's anti-tumor and immunity mechanism, and the current achievement of standard chemoradiotherapy combined with immunotherapy, to explore the potential benefits to GBM patients.