Clinicopatholigical differences between patients with adenocarcinoma of esophagogastric junction and gastric cancer without esophagogastric junction invasion
10.3760/cma.j.issn.1673-4203.2019.12.009
- VernacularTitle: 食管胃结合部癌与非结合部胃癌临床病理特征差异
- Author:
Run XU
1
;
Jian LI
;
Dengmin HU
;
Tuping GONG
;
Yao ZHANG
Author Information
1. Department of General Surgery, the Third Hospital of Mianyang, Mianyang 621000, China
- Publication Type:Journal Article
- Keywords:
Esophagogastric junction;
Adenocarcinoma;
Pathology clinical;
Helicobacter pylori;
Body mass index
- From:
International Journal of Surgery
2019;46(12):830-834
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the clinicopatholigical differences between patients with adenocarcinoma of esophagogastric junction (AEG) and gastric cancer without esophagogastric junction invasion, and relationship between the two type cancers and Helicobacter pylori (Hp) infection, body mass index.
Methods:A retrospective analysis was performed on 577 cases of gastric cancer patientsin the Third Hospital of Mianyang from December 2013 to February 2018.Patients were divided into AEG group (n=218) and gastric cancer without esophagogastric junction invasion group (n=359) according to location of neoplasm. The age, gender, body mass index, Hp infection, pathological stage, operative type and blood loss in operation of patients between two groups were compared, and the relationship between the two type cancers and Hp infection, body mass index was analyzed by logistic regression, OR and 95%CI: was calculated.
Results:AEG patients were accounted for 37.8%, and had a relatively higher percentage of males, older age, more open surgery, surgery duration and perioperative transfusion, and a relatively lower percentage of Hp infection and family history of gastric cancers. When adjusted for age, gender and family history, the frequency of infection with Hp was higher in patients with gastric cancer without esophagogastric junction invasion, the OR was 1.73(95%CI: 1.22-2.46, P<0.05), while the differences of BMI was not significant between patents in two groups.
Conclusion:The different characteristics of AEG and gastric cancer without esophagogastric junction invasion cases have implications for the development of guiding strategies for diagnosis and treatment of gastric cancer patients based on tumor location.
