Analysis of the significance of cerebral perfusion imaging combined with CT angiography in the diagnosis and treatment plan of patients with ischemic stroke
10.3760/cma.j.issn.1673-4904.2019.12.011
- VernacularTitle: 脑灌注成像技术联合CT血管造影对缺血性脑卒中患者的诊断及治疗计划制定的意义
- Author:
Huihong FU
1
;
Xuehong ZHANG
;
Min LI
;
Yong HUANG
Author Information
1. Department of Radiology, Taizhou First People′s Hospital, Zhejiang Taizhou 318020, China
- Publication Type:Journal Article
- Keywords:
Cerebral perfusion imaging;
CT angiography;
Ischemic stroke;
Diagnostic efficacy
- From:
Chinese Journal of Postgraduates of Medicine
2019;42(12):1103-1107
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the significance of cerebral perfusion imaging combined with CT angiography (CTA) in the diagnosis and treatment plan of patients with ischemic stroke.
Methods:Total of 44 patients with acute cerebral infarction were enrolled in Taizhou First People′s Hospital from January 2018 to September 2018. Cerebral perfusion imaging and CTA examination were performed simultaneously within 12 h after the onset of the disease. The images of perfusion imaging were processed using an image workstation to measure the level of perfusion parameters in the ischemic region of the patient′s brain. The head and neck of the patient were measured by CTA. The angiography was performed, and the cerebral angiography results of all patients were as the gold standard. The clinical diagnosis and diagnostic efficacy of different examination methods in patients with ischemic stroke was observed and compared, and the differences in the parameters of perfusion imaging between different perfusion abnormal areas and normal control areas were compared.
Results:When patients′ cerebral angiography and single-photon emission computed tomography (SPECT) was as the gold standard for comparison, cerebral blood flow (CBF) and mean transit time (MTT) had the highest accuracy among all parameters of perfusion imaging. The accuracy rate of perfusion imaging+CTA was 93.2%, with a specificity of 100.0% and a sensitivity of 90.1%, which was significantly higher than that of the clinical efficacy of single diagnosis.
Conclusions:Perfusion imaging combined with CTA can provide important supplementary reference information for clinical diagnosis and treatment of patients with ischemic stroke.
