The status and health risk assessment of dietary fipronil contamination among 20 provinces of China
10.3760/cma.j.issn.0253-9624.2019.12.008
- VernacularTitle: 中国20个省份膳食氟虫腈污染状况及健康风险评估
- Author:
Dawei CHEN
1
;
Shaohua LI
;
Bing LYU
;
Yunfeng ZHAO
;
Jingguang LI
;
Yongning WU
Author Information
1. National Health and Health Commission Key Laboratory of Food Safety Risk Assessment/Food Safety Research Unit (2019RU014) of Chinese Academy of Medical Science/China National Center for Food Safety Risk Assessment, Beijing 100021, China
- Publication Type:Journal Article
- Keywords:
Pesticides;
Diet surveys;
Chromatography;
Mass spectrometry;
Fipronil
- From:
Chinese Journal of Preventive Medicine
2019;53(12):1242-1246
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To understand the status and health risk assessment of dietary fipronil contamination among 20 provinces of China.
Methods:A total of 13 kinds of dietary samples in Chinese total diet study include cereals, legumes, potatoes, meats, eggs, aquatics, dairies, vegetables, fruits, sugars, beverages and water, alcohols, condiments and their corresponding products. Among them, condiments were used in the preparation of 12 other sample categories; thus, the actual mixed dietary samples of each province covered 12 groups. A total of 240 mixed dietary samples were collected from 20 provinces in China from 2009 to 2013. After the sample extraction and cleanup, dietary samples were analyzed for the residues of fipronil and its metabolites to obtain the contamination levels of fipronil residues using liquid chromatography-high resolution mass spectrometry. The dietary intake of adult residents was estimated based on food consumption of general population of China.
Results:Among the 240 dietary samples, the detection rate of fipronil was 10.4% (25 samples), and the detection rates of fipronil metabolites, i.e. fipronil desulfinyl, fipronil sulfone and fipronil sulfide were 20.4% (49 samples), 40.0% (96 samples) and 8.8% (21 samples), respectively. According to the dietary exposure analysis, the average lower and upper dietary exposure levels of fipronil residues in adult residents of China were 11.34 and 12.35 ng·kg-1·d-1, accounting for 5.7% and 6.2% of acceptable daily intake (ADI), respectively. The highest adult dietary intake of fipronil residues was found in Hunan province, with a value of 72.98 ng·kg-1·d-1, accounting for 36.5% of ADI. Vegetables were the main dietary source of fipronil residues, which contributed to 71.0% of the total intake dose.
Conclusion:Fipronil residues were detected in varying degrees in dietary samples, yet the health risk caused by the dietary intake of adult residents among 20 provinces of China is low.
