Echocardiographic evaluation of the patients with borderline pulmonary hypertension
10.3760/cma.j.issn.1004-4477.2019.12.001
- VernacularTitle: 临界肺循环高压患者的心脏超声评价
- Author:
Wenying JIN
1
;
Chao YU
;
Xinran SHI
;
Hong CHEN
;
Tiangang ZHU
Author Information
1. Department of Cardiology, Beijing Key Laboratory of Early Prediction and Intervention of Acute Myocardial Infarction, Peking University People′s Hospital, Beijing 100044, China
- Publication Type:Clinical Trail
- Keywords:
Echocardiography;
Pulmonary hypertension;
Mean pulmonary artery pressure
- From:
Chinese Journal of Ultrasonography
2019;28(12):1013-1018
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To analyze and compare the changes of cardiac structure and function in patients with borderline pulmonary hypertension.
Methods:Echocardiographic data of 617 outpatients from February to October 2018 in Peking University People′s Hospital were retrospectively analyzed. According to the estimated mean pulmonary artery pressure (mPAP), the patients were divided into normal group (mPAP<19 mmHg), borderline group (19 mmHg≤mPAP<25 mmHg) and elevated group (mPAP≥25 mmHg).
Results:①Compared with normal group，the patients were older in borderline group and elevated group[(39.2±10.1)years old vs (46.5±13.5)years old vs (51.8±14.2)years old，all P<0.001] and the proportions of male were relatively lower (69.9% vs 58.9% vs 54.4%，all P<0.01). The incidences of smoking，drinking and cardiovascular complications increased significantly. ②Compared with normal group，the left atrium[(30.2±8.2)ml/m2 vs (34.5±9.7)ml/m2，P<0.001]，left ventricle[(57.4±11.6)ml/m2 vs (60.6±12.5)ml/m2，P<0.01]and right atrium[(19.5±5.9)ml/m2 vs (22.6±7.0)ml/m2，P<0.001] were enlarged in borderline group.Left ventricular global long-axis strain (GLSLV) increased[(-20.1±2.5)% vs (-21.1±3.1)%，P<0.001]，but the long-axis strain in the middle segment of right ventricular free wall (GLSRVFWmid) decreased[(-31.4±6.6)%对(-27.2±8.8)%，P<0.001] in borderline group.Meanwhile，left ventricular diastolic function was impaired. ③Age，sex，right atrial volume，right ventricular area，RV-S′，GLSLV，GLSRVFWmid and mitral valve E/e′ were independent risk factors for mPAP elevation.
Conclusions:Early changes of cardiac structure and function exist in the patients with borderline pulmonary hypertension. Echocardiography is critical for the early diagnosis and follow-up monitoring of pulmonary hypertension.
