Feasibility and efficacy of indocyanine green used in laparoscopic gastrectomy for advanced gastric cancer patients
10.3760/cma.j.issn.0253-3766.2019.12.005
- VernacularTitle: 吲哚菁绿在进展期胃癌腹腔镜手术中的安全性和有效性
- Author:
Shuai MA
1
;
Yibin XIE
1
;
Hongmei ZENG
2
;
Quan XU
1
;
Yuxin ZHONG
1
;
Hao LIU
1
;
Fuhai MA
1
;
Fei ZHAO
3
;
Huan LI
4
;
Yang LI
1
;
Yantao TIAN
1
Author Information
1. Department of Pancreatic and Gastric Surgery, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China
2. Office for Cancer Registry, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China
3. Department Ⅱ of General Surgery, Handan Central Hospital, Handan 056001, China
4. Department of General Surgery, North China Petroleum General Hospital, Hebei Medical University, Renqiu 062552, China
- Publication Type:Journal Article
- Keywords:
Gastric neoplasms;
Indocyanine green;
Lymphadenectomy
- From:
Chinese Journal of Oncology
2019;41(12):904-908
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To identify the feasibility and efficacy of indocyanine green (ICG) used in laparoscopic gastrectomy for advanced gastric cancer patients.
Methods:From December 2018 to August 2019, the clinical data of 82 patients preoperatively diagnosed as advanced gastric cancer undergoing laparoscopic radical gastrectomy were retrospectively analyzed. These patients were divided into ICG group(n=38) and a historical control group (non-ICG group, n=44). The number of retrieved lymph nodes, operation time, blood loss, hospital stay, fever time, evacuation time and complications were compared between these two groups.
Results:The operation time [(172.8±45.8) min vs (162.6±45.7) min], blood loss [(80.1±91.9) ml vs (78.6±89.8) ml], hospital stay [(7.0±2.0) d vs (7.5±2.4) d], fever time [(2.3±1.2) d vs (2.9±1.9) d], evacuation time [(3.4±0.8) d vs (3.4±1.1) d] and incidence of complications (5.3% vs 9.1%) were not significantly different between the ICG and historical control groups (P>0.05). The number of retrieved lymph nodes in ICG group was significantly increased compared with that of the historical control group (46.5 vs 33.0, P=0.005).
Conclusions:The ICG method applied in lymph node dissection of laparoscopic radical gastrectomy is safe. Moreover, ICG might elevate the efficiency of regional lymph node dissection.
