The U-shaped relationship between hemoglobin concentration and stroke
10.3760/cma.j.issn.1006-7876.2019.12.012
- VernacularTitle: 血红蛋白水平与脑卒中的"U"形曲线关系
- Author:
Shengde LI
1
;
Bin PENG
2
Author Information
1. Department of Neurology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100730, China
2. Department of Neurology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing 100730, China
- Publication Type:Review
- Keywords:
Stroke;
Brain ischemia;
Intracranial hemorrhage;
Hemoglobins;
Anemia;
Prognosis
- From:
Chinese Journal of Neurology
2019;52(12):1068-1072
- CountryChina
- Language:Chinese
-
Abstract:
Anemia and hyperhemoglobin are not common stroke risk factors, and the association between hemoglobin concentration and stroke remains inconclusive. Through searching the literature, the impact of hypo- and hyper-hemoglobin on the risks of incident stroke, mortality, and poor functional prognosis was analyzed. The review revealed a U-shaped relationship between hemoglobin and the risks of incidental ischemic stroke, and mortality of ischemic stroke and intracranial hemorrhage, separately. However, the optimal hemoglobin concentration was undetermined.