Dysphagia in patients with middle cerebral artery infarction: A retrospective diffusion tensor imaging study
10.3760/cma.j.issn.0254-1424.2019.12.014
- VernacularTitle: 基于弥散张量成像分析大脑中动脉脑梗死患者吞咽障碍的回顾性研究
- Author:
Lingyan WANG
1
;
Aiqun SHI
1
;
Ying ZHAO
1
;
Daming WANG
2
;
Hong HONG
1
;
Jie LI
3
;
Jie SONG
4
Author Information
1. Department of Rehabilitation Medicine, The Affiliated Traditional Chinese Medicine Hospital of Zhejiang University of Traditional Chinese Medicine, Jinhua 321017, China
2. Department of Rehabilitation Medicine, The First Affiliated Hospital of Zhejiang University, Hangzhou 310006, China
3. Department of MRI, The Affiliated Traditional Chinese Medicine Hospital of Zhejiang University of Traditional Chinese Medicine, Jinhua 321017, China
4. Department of Rehabilitation Medicine, No. 1 People′s Hospital of Huzhou City, Huzhou 313000, China
- Publication Type:Clinical Trail
- Keywords:
Cerebral infarction;
Dysphagia;
Diffusion tensor images;
Insulae;
Cerebral peduncles
- From:
Chinese Journal of Physical Medicine and Rehabilitation
2019;41(12):935-940
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To determine the subcortical areas associated with post-stroke dysphagia and its recovery using diffusion tensor images.
Methods:Ten patients with middle cerebral artery lesions and dysphagia were selected into the dysphagia group, while another 10 counterparts without dysphagia were chosen for the non-dysphagia group. The ratios of diffuse anisotropy (rFAs) in eleven regions of interest (ROIs) on both the healthy and affected sides were recorded and compared between the two groups. One and 3 months later, the rFA values of the dysphagia group were again measured and the rFAs were related with dysphagia outcomes and severity using Spearman correlation analysis.
Results:Comparing the rFAs of the 11 ROIs between the two groups revealed significant differences between the insulae of the dysphagia group and the non-dysphagia group. Three months later the rFA values of the insulae, cerebral peduncles and superior cerebellar peduncles had increased significantly in the dysphagia group. The average dysphagia outcome and severity score of the dysphagia group was significantly lower one month after the treatment than 3 months later. Moreover, the outcome and severity score was found to be significantly correlated with the rFA values of the insulae and of the superior cerebellar peduncles one month after the treatment, but with that of the cerebral peduncles only after 3 months.
Conclusion:Dysphagia within one month of the onset of infarction is related to the insulae, the cerebral peduncles and the superior cerebellar peduncles. After 3 months it is associated with the cerebral peduncles.
