Bacterial biofilm and chronic wound infection
10.3760/cma.j.issn.1009-2587.2019.12.003
- VernacularTitle: 细菌生物膜与慢性创面感染
- Author:
Jia′ao YU
1
;
Xinxin GAO
Author Information
1. Department of Burn Surgery, the First Hospital, Jilin University, Changchun 130021, China
- Publication Type:Journal Article
- Keywords:
Bacteria;
Biofilms;
Infection;
Chronic wound
- From:
Chinese Journal of Burns
2019;35(12):842-847
- CountryChina
- Language:Chinese
-
Abstract:
Bacteria usually colonize, reproduce, and grow aggressively on chronic wounds in the form of biofilm. Different from free bacteria, bacteria in biofilm exhibit unique mechanism in epigenetics and biological behavior, especially in resistance to antibiotics and host immunity. In this article, we introduce the composition and structural function of bacterial biofilm, expound the drug-resistance mechanism of bacterial biofilm, discuss the clinical characteristics of bacterial biofilm infection wound and the diagnosis method of biofilm, and analyze the treatment strategy for bacterial biofilm. It is suggested that clinicians should pay more attention to bacterial biofilm infection and advocate in-depth study of bacterial biofilm in order to improve the quality of managing chronic wounds.
