Therapeutic effects of endoscopic foam sclerotherapy for bleeding internal hemorrhoids
10.3760/cma.j.issn.1007-5232.2019.12.009
- VernacularTitle: 肠镜下泡沫硬化剂治疗出血性内痔的疗效评估
- Author:
Feng SHEN
1
;
Chunying QU
1
;
Yi ZHANG
1
;
Min ZHOU
1
;
Zhenzhong DENG
1
;
Huali ZHU
2
;
Jingyang ZHU
3
;
Guangyu CHEN
4
;
Xi ZHANG
4
;
Leiming XU
1
Author Information
1. Department of Gastroenterology, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai 200092, China
2. Department of Gastroenterology, Jiaxing Second Hospital, Jiaxing 314000, China
3. Department of Gastroenterology, Minhang Traditional Chinese Medicine Hospital, Shanghai 201103, China
4. Clinical Research Unit, XinHua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai 200092, China
- Publication Type:Journal Article
- Keywords:
Hemorrhoids;
Sclerosing solutions;
Hemostasis, endoscopic;
Sclerotherapy
- From:
Chinese Journal of Digestive Endoscopy
2019;36(12):917-922
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To evaluate the safety and efficacy of foam sclerotherapy for bleeding internal hemorrhoids.
Methods:Consecutive adult patients (aged 18-60 years) with bleeding hemorrhoids were prospectively enrolled between March 2017 and March 2018. All patients were randomly assigned to the foam sclerotherapy (FS) group and the liquid sclerotherapy (LS) group. The foam and liquid sclerotherapy of hemorrhoids nucleus was performed by cap-assisted colonic endoscopy.
Results:A total of 108 patients were enrolled, including 62 males (57.4%) with mean age of 44.0±7.6 years. There was no significant difference in gender, age, or body mass index between the FS (n = 55) group and the LS (n =53) group. The total amount of lauromacrogol injection in the FS group was 3.7±0.9 mL, which was significantly lower than that in the LS group (8.0±2.2 mL, P<0.001). In the LS group, 8 patients (15.1%) developed bleeding after needle removal, which was significantly higher than that in the FS group [5.5%(3/53), P=0.022]. Significant pain was found in 2 patients (3.8%) in the LS group and 0 in the FS group (P= 0.025). The short-term cure rate and effective rate of the FS group were 87.3% (48/55) and 9.1% (5/55), while those were 69.8% (37/53) and 22.6% (12/53) in the LS group, respectively (P=0.046).
Conclusion:Foam sclerotherapy is safe and effective in the treatment of bleeding internal hemorrhoids.
