Recent advances of molecular biology technology in Chlamydia trachomatis detection
10.3760/cma.j.issn.1009-9158.2019.12.017
- VernacularTitle: 沙眼衣原体分子生物学检测技术进展及应用
- Author:
Junjie QIU
1
;
Likuan XIONG
2
,
3
Author Information
1. Center of Clinical Laboratory Medicine, the First Affiliated Hospital of Jinan University, Jinan University, Guangzhou 510630, China
2. Shenzhen Key Laboratory of Birth Defects
3. Central Laboratory, Baoan Maternal and Child Health Hospital, Jinan University, Shenzhen 518100, China
- Publication Type:Review
- Keywords:
Chlamydia trachomatis;
Polymerase chain reaction;
Nucleic acid amplification techniques;
Microarray analysis;
Multilocus sequence typing
- From:
Chinese Journal of Laboratory Medicine
2019;42(12):1067-1071
- CountryChina
- Language:Chinese
-
Abstract:
Chlamydia trachomatis (CT) is a prevalent pathogen clinically causing trachoma and sexually transmitted diseases. This review presents the progress and application of molecular biology techniques in CT detection according to different types of methodologies, mainly including real-time PCR amplification tests, nucleic acid isothermal amplification tests, PCR-hybridization, sequence analysis and compare their advantages and disadvantages. The recent developments of the point-of-care testing for CT are also briefly introduced in this paper.
