Research progress in immunoregulatory effects of adipose mesenchymal stem cells
10.3760/cma.j.issn.0254-5101.2019.12.012
- VernacularTitle: 脂肪间充质干细胞免疫调节作用的研究进展
- Author:
Huiqing HU
1
;
Xinguo HOU
;
Li CHEN
Author Information
1. Department of Endocrinology, Qilu Hospital of Shandong University, Institute of Endocrine and Metabolic Diseases of Shandong University, Key Laboratory of Endocrine and Metabolic Diseases, Shandong Province Medicine & Health, Jinan 250012, China
- Publication Type:Review
- Keywords:
ADSC;
Immunocyte;
Immunoregulation
- From:Chinese Journal of Microbiology and Immunology
2019;39(12):958-964
- CountryChina
- Language:Chinese
-
Abstract:
Adipose derived mesenchymal stromal cells (ADSC) are pluripotent stem cells isolated from adipose tissue and have great application potential in regenerative medicine for their rich sources of derivation, relatively less trauma when sampling and few ethical problems. ADSC have preferable immunomodulatory capacity, and can regulate the immunologic functions of dendritic cells, macrophages, NK cells, NKT cells, B lymphocytes and T lymphocytes. In order to better understand the role of ADSC in immunoregulation, this paper systematically reviewed the immunomodulatory effects of ADSC on several representative immune cells.
