Research progress of the role of long non-coding RNA in the development of thyroid cancer
10.3760/cma.j.issn.2095-4255.2019.12.020
- VernacularTitle: 长链非编码RNA在甲状腺癌发生发展过程中作用的研究进展
- Author:
Qiushi TIAN
1
;
Lijun FAN
;
Dianjun SUN
Author Information
1. Center for Endemic Disease Control, Chinese Center for Disease Control and Prevention, Harbin Medical University, Harbin 150081, China
- Publication Type:Review
- Keywords:
Thyroid cancer;
Long non-coding RNA;
Pathogenesis;
Biomarkers
- From:
Chinese Journal of Endemiology
2019;38(12):1023-1027
- CountryChina
- Language:Chinese
-
Abstract:
Long non-coding RNA (lncRNA) is a type of non-coding RNAs (ncRNA), and it involved in a wide range of biological processes. In recent years, the role of lncRNA in the development and progression of tumors has been widely concerned by the field of medical with the further researches. Mounting evidence also shows that many lncRNAs have altered expression in various types of human cancer and involved in the progress of tumor by multi ways. Thyroid cancer is a complex disease of uncertain origin, and it is lack of effective diagnosis, treatment and prognosis biomarkers. Therefore, finding the association between lncRNA and thyroid cancer is very important and helpful for clarifying the pathogenesis and finding new effective biomarkers for this disease.
