Analysis of urinary iodine in pregnant women with thyroid disease in Shenzhen
10.3760/cma.j.issn.2095-4255.2019.12.015
- VernacularTitle: 深圳市妊娠合并甲状腺疾病妇女的尿碘分析
- Author:
Xiaoyu HONG
1
;
Yali DAI
;
Weixing ZHANG
;
Qian XIE
;
Lingchuan HAN
;
Peixian WU
;
Donghui LU
Author Information
1. Department of Endocrinology, Peking University Shenzhen Hospital, Shenzhen 518000, China
- Publication Type:Clinical Trail
- Keywords:
Thyroid diseases;
Pregnancy complications;
Urine;
Iodine
- From:
Chinese Journal of Endemiology
2019;38(12):1003-1005
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To study the urinary iodine level of pregnant women with thyroid disease in Shenzhen, and to provide scientific basis for rational iodine supplementation.
Methods:A total of 170 pregnant women with thyroid diseases who visited Department of Endocrinology, Peking University Shenzhen Hospital from January 2017 to March 2019 were selected as the subjects, they were divided into hyperthyroidism group (84 cases) and non-hyperthyroidism group (86 cases) according to whether they had hyperthyroidism or not. Morning urine sample was collected under normal dietary conditions; urinary iodine was detected by peroxyacetic acid tetramethylbenzidine oxidation colorimetry. Urinary iodine < 150 μg/L was iodine deficiency and 150-249 μg/L was appropriate iodine.
Results:The median of urinary iodine of pregnant women with thyroid disease in Shenzhen was 143.9 μg/L, which was slightly lower than the lowest limit of the appropriate iodine level. The median of urinary iodine in hyperthyroidism group was 116.6 μg/L, which was at the iodine deficiency level; the median of urinary iodine in non-hyperthyroidism group was 181.6 μg/L, which was at the appropriate iodine level. There was significant difference in urinary iodine levels between hyperthyroidism group and non-hyperthyroidism group (Z =-2.261, P < 0.05).
Conclusion:The urinary iodine of pregnant women with hyperthyroidism in Shenzhen is slightly low.
