Clinical and neuroimaging features in 6 patients with corticobasal syndrome
10.3760/cma.j.issn.0578-1426.2019.12.007
- VernacularTitle: 皮质基底节综合征六例临床及影像学特点
- Author:
Qingli SUN
1
;
Qiong YANG
;
Aping SUN
;
Yu FU
;
Dongsheng FAN
Author Information
1. Department of Neurology, Perking University Third Hospital, Beijing 100191, China
- Publication Type:Case Reports
- Keywords:
Corticobasal syndrome;
Clinical features;
Neuroimaging
- From:
Chinese Journal of Internal Medicine
2019;58(12):905-907
- CountryChina
- Language:Chinese
-
Abstract:
The clinical and imaging data in 6 patients with corticobasal syndrome were retrospectively analyzed. Six patients presented asymmetric clinical symptoms, including 5 with cognitive impairment, 6 with emotional disorders, 2 with cortical sensory deficit, 5 with lalopathy, and 4 with apraxia. All patients developed limb dystonia and limb or trunk stiffness, 4 with tumble, 4 with bradykinesia, and 2 with tremor. Brain magnetic resonance imaging (MRI) showed that 4 patients had unilateral cerebral atrophy and 2 had mild atrophy of bilateral hippocampus. Localized low glucose metabolism in the unilateral cerebral lobe was seen in four patients by positron emission computed tomography (PET) examination, suggesting that PET is helpful for the diagnosis of corticobasal syndrome.
