Studies on efficacy and dosage for schoolchildren of some anthelminthic drugs.
10.3347/kjp.1974.12.2.147
- Author:
Jung Kyun CHU
1
;
You Jung CHO
Author Information
1. Department of Parasitology, School of Medicine, Kyung Hee University, Korea.
- Publication Type:Original Article
- MeSH:
parasitology-helminth-nematoda-Ascaris lumbricoides;
pyrantel pamoate;
piperazine adipate;
santonin-kainic acid complex;
chemotherapy;
drug evaluation;
body weight;
body surface;
age
- From:The Korean Journal of Parasitology
1974;12(2):147-156
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
The evaluation of the effects of anthelmintic drug dose was done by the eggs reduction and the eggs negative conversion rate. The drug dose according to the age of the patient was estimated by the formula of Augsberger, the dose according to the body weight of patient was estimated by the Rule of Six, and the dose to the body surface of the patient was estimated by the formula of Costeff. It is considered that the application of the drug dose according to the age of the patient resulted in reduction of dose in the younger patient, and resulted in the excess dose in older patient. The application of the drug dose according to the body weight also resulted in the reduction of dose in the lighter patient and the excess dose in the heavier patient. It is suggested that the application of drug dose according to the body surface is more reasonable than those by the age and the body weight. The value of this application was also proved to be medium value between those of age method and body weight method.
